Cancer epigenetics
نویسندگان
چکیده
منابع مشابه
Epigenetics in diagnosis of colorectal cancer
Colorectal cancer (CRC) is a third most common epithelial carcinoma. CRC is known to develop from the early precancerous lesion to full blown malignancy via definite phases due to cumulative mutations and aberrant methylation of number of genes. The use of serum biomarkers that is non-invasive to discriminate cancer patients from healthy persons will prove to be an important tool to improve the...
متن کاملCancer Epigenetics
Downlo 13th American Association of Cancer Research (AACR) Special Conference on Cancer Epigenetics was n San Juan, Puerto Rico, on January 20–23, 2010. This event heralded insights arising from the large cing efforts within the NIH Epigenetics Roadmap Project and the Cancer Genome Atlas Project, as well ortant new discoveries in the basic biology of epigenetics and results of epigenetic drug c...
متن کاملCancer epigenetics.
The field of cancer epigenetics is evolving rapidly on several fronts. Advances in our understanding of chromatin structure, histone modification, transcriptional activity and DNA methylation have resulted in an increasingly integrated view of epigenetics. In response to these insights, epigenetic therapy is expanding to include combinations of histone deacetylase inhibitors and DNA methyltrans...
متن کاملThe Role of Epigenetics in Cancer Drug Resistance
Cancer is caused by aberrant genetic and epigenetic changes in genes expression. DNA methylation, histone modification, and microRNAs gene deregulation are the most known epigenetic changes in different stages of cancer. Since every tumor has its own specific epigenome, any abnormal pattern is a potential biomarker for classification of different types of tumors. Despite, tumorigenesis, abnorma...
متن کاملEpigenetics in Cancer Metastasis
Cancer has been traditionally regarded as a disease caused by genetic mutations. However, since the development of epigenetic and our better understanding of cancer itself, scientists now recognize the role of epigenetic factors in cancer. Cancer metastasis, the spread of cancer cell to secondary sites, is one of the most dangerous events in late cancer stages. With no exception, epigenetic fac...
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ژورنال
عنوان ژورنال: Oncogene
سال: 2003
ISSN: 0950-9232,1476-5594
DOI: 10.1038/sj.onc.1206774